Advances and Applications in Gene Silencing
10.3969/j.issn.1003-4706.2018.01.030
- VernacularTitle:基因沉默策略及其应用研究进展
- Author:
Xiao-Nan ZHOU
1
;
Xue-Lan SONG
;
Yuan YANG
;
Chen-Jing MA
;
Fang-Yan HE
Author Information
1. 云南中医学院药理教研室
- Keywords:
Ribozyme technology;
Antisense oligonucleic acid technology;
Gene knockout;
RNA interference technologywords
- From:
Journal of Kunming Medical University
2018;39(1):131-135
- CountryChina
- Language:Chinese
-
Abstract:
Gene silencing is a phenomenon in which the specific genes in organisms are not expressed or reduced for various reasons. It is an important mechanism to control gene expression by epigenetic control. At present, scientists intend to explore the treatment of difficult diseases through gene silencing technology,and the research has become a hot spot. With the rapid development of gene engineering, gene silencing technology has been replaced by new technologies. This paper aims to introduce the ribozyme technology, antisense oligonucleic acid technology, gene knockout,RNA interference technology and their applications in gene silencing technology.
