Development of exosomes biogenesis and secretion mechanisms
10.11855/j.issn.0577-7402.2017.12.16
- VernacularTitle:外泌体生成和分泌机制的研究进展
- Author:
Yue ZHAO
1
;
Chao WANG
;
He-Zhong CHEN
Author Information
1. 200438上海,海军军医大学附属长海医院胸外科
- Keywords:
exosomes;
cell communication;
regulation
- From:
Medical Journal of Chinese People's Liberation Army
2017;42(12):1106-1109
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are nano-sized membrane vesicles (30-100nm in diameter) actively secreted by many cell types and generally exist in many body fluids that contain a variety of cargos,such as protein,lipid and nucleic acid.Exosomes play an important role in cross-communication between different cells and closely associate with the development,treatment and prognostic of many diseases.Recently,exosomes have becoming a hot spot in medical research.An overview of current understanding in biogenesis and secretion mechanism,as well as the regulation of exosomes has been laid in present paper.
