Research advances of alpha-enolase in tumors
10.3760/cma.j.issn.1673-422X.2018.05.008
- VernacularTitle:α-烯醇化酶在肿瘤中的研究进展
- Author:
Xin XU
1
;
Bo CHEN
Author Information
1. 安徽医科大学第一附属医院胃肠外科
- Keywords:
Phosphopyruvate hydratase;
Neopasmas;
Immunotherapy
- From:
Journal of International Oncology
2018;45(5):288-291
- CountryChina
- Language:Chinese
-
Abstract:
Alpha-enolase(ENO1) is one of the key enzymes in glycolysis,which plays an important role in tumor metabolism.Accumulating evidences show that ENO1 is overexpressed in many tumor tissues,promoting cell proliferation,apoptosis,invasion and metastasis.It is also closely associated with drug resistance and tumor immunotherapy.As a novel potential target in tumor therapy,ENO1 has drawn great attention.
