Study of anticoagulant protocols in patients undergoing non-cardiac surgery after percutaneous coronary intervention
10.3969/j.issn.1671-8348.2018.05.020
- VernacularTitle:PCI术后患者再行非心脏手术的抗凝方案研究
- Author:
Hui LIU
1
;
Bo GAO
;
Hui ZHAO
;
Yan WANG
Author Information
1. 天津市天津医院心血管内科 30000
- Keywords:
percutaneous coronary intervention;
acute coronary syndrome;
non-cardiac surgery;
anti-coagulation therapy
- From:
Chongqing Medicine
2018;47(5):642-643,646
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the anticoagulant treatment protocols during perioperative period in the patients undergoing non-cardiac surgery after percutaneous coronary intervention(PCI).Methods Seventy-one patients undergoing non-cardiac surgery after PCI in this hospital from January 2014 to June 2016 were selected and given the low molecular weight heparin treatment before elective surgery.After surgery,the patients were divided into the anti-coagulation group and non-anticoagulation group.Then the occurrence situation of postoperative major adverse cardiac events was observed.Results The general indicators such as sex,age,complicating hypertension and diabetes and stent length and complication situation had no statistical differences between the two groups(P＞0.05).Within postoperative 7 d,there were 3 cases of unstable angina pectoris in the anti-coagulation group and 10 cases in the non-anticoagulation group,the difference between them was statistically significant(P＜0.05).The creatine phosphate kinase(CK) level at postoperative 24 h in the anti-coagulation group and non-anticoagulation group was significantly increased compared with pre-operation(P＜0.05),and the levels of CK-MB and cTnI had an increasing trend compared with before operation,but the difference was not statistically significant(P＞0.05).The preoperative and postoperative CK,CK-MB and cTnI levels had no statistical difference between the two groups(P0.05).Conclusion The anticoagulation therapy during perioperative priod in the patients undergoing non-cardiac surgery within 1 year after PCI can obviously reduce the occurrence of major adverse cardiac events.
