Progress of molecular pathogenesis of extranodal natural killer/T-cell lymphoma
10.3760/cma.j.issn.1009-9921.2018.09.018
- VernacularTitle:结外NK/T细胞淋巴瘤分子机制研究进展
- Author:
Wenjuan YIN
1
;
Meijuan WU
Author Information
1. 310022 杭州,浙江省肿瘤医院病理科;浙江省头颈肿瘤转化医学研究重点实验室
- Keywords:
Lymphoma,extranodal NK-T-cells;
Molecular pathogenesis
- From:
Journal of Leukemia & Lymphoma
2018;27(9):570-573
- CountryChina
- Language:Chinese
-
Abstract:
Extranodal nature killer/T cell lymphoma (ENKTCL) is a highly aggressive non-Hodgkin lymphoma (NHL) with a high mortality. ENKTCL is epidemic in Asia and Latin America, especially in China, Japan and South Korea. EBV has been proved to be associated closely with ENKTCL; however, specific molecular mechanism which can explain how the neoplasm develops is still unclear. Chinese population seems to be more susceptible to this lymphoma and Chinese scientists have made great contributions to the pathogenesis and the treatments of ENKTCL. This review mainly introduces the recent progress of molecular pathogenesis of ENKTCL.
