Periprosthetic joint infection after artificial joint replacement and preoperative anemia.
10.3969/j.issn.1003-0034.2018.10.019
- Author:
Wei WANG
1
;
Jun LIU
1
;
Sheng-Hu ZHOU
1
;
Sheng-Gui LI
1
;
Yong-Jie QIAO
1
;
Jian LIU
1
;
Ping ZHEN
2
,
3
Author Information
1. Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China.
2. Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China; zhenpingok@
3. com.
- Publication Type:Journal Article
- Keywords:
Anemia;
Arthroplasty, replacement;
Prosthesis-related infections;
Review literature
- From:
China Journal of Orthopaedics and Traumatology
2018;31(10):971-975
- CountryChina
- Language:Chinese
-
Abstract:
Periprosthetic joint infection is the most serious complication after artificial joint arthroplasty. Epidemiological investigation has indicated that perioperative anemia is an independent risk factor for periprosthetic joint infection, which could play an important role by suppressing cellular mechanisms and autoimmune functions. Many domestic and overseas scholars have studied the relationship between periprosthetic joint infection and postoperative anemia, but the relationship between preoperative anemia and periprosthetic joint infection is relatively rare. However, preoperative anemia can reduce the C3b receptor on surface of red blood cells, decrease immune function of the body, increase blood-borne infection, prolong postoperative rehabilitation time, and lead to periprosthetic joint infection. For patients with preoperative anemia, prophylactic antibiotics could be used to prevent. And complement chalybeate used before operation, correct anemia by hemopoietin, treat chronic complications influence by hemoglobin production and improve patient's own immune status, blood transfusion treatment for patients with blood transfusion indications are performed. It could be better prevent occurrence of periprosthetic joint infection after total joint arthroplasty, and reducing chance of secondary or multiple renovations.
