Chemcial constituents of Eclipta prostrata.
10.19540/j.cnki.cjcmm.20180625.001
- Author:
Wen LI
1
;
Xu PANG
2
;
Li-Feng HAN
2
;
Ying ZHOU
1
;
Yi-Min CUI
1
Author Information
1. School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
2. Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
- Publication Type:Journal Article
- Keywords:
Asteraceae;
Eclipta prostrata;
alkaloid;
coumarin;
flavone;
lignin;
pentacyclic triterpene;
thiophene
- From:
China Journal of Chinese Materia Medica
2018;43(17):3498-3505
- CountryChina
- Language:Chinese
-
Abstract:
A total of twenty-two compounds were isolated from the 95% EtOH extract of Eclipta prostrata by various purification steps, and their structures were established as ecliptalignin A (1),ecliptasaponin Ⅰ (2), ecliptasaponin Ⅱ (3), echinocystic acid (4), 3-oxo-16α-hydroxy-olean-12-en-28-oic acid (5), acacetin-7--rutinoside (6), luteoloside (7), apigenin (8), luteolin (9), acacetin (10), skullcapflavone Ⅱ (11), kaempferol (12), kaempferide (13), quercetin (14), 4',7-dihydroxyl-3',6'-dimethoxylisoflavone-7--glucoside (15), ecliptal (16), 5-hydroxymethyl-(2,2',5',2″)-terthienyl tiglate (17), psoralen (18), isopsoralen (19), wedelolactone (20), crinumaquine (21), and 2,3,9,12-tetramethoxyprotoberberine (22) mainly based on the spectroscopic techniques, of which 1 was a new lignin analogue, and 5, 6, 10-13, 15, 18, 19, 21 and 22 were isolated form this plant for the first time.