Advances in the molecular mechanisms of perineural invasion in salivary adenoid cystic carcinoma.

VernacularTitle:涎腺腺样囊性癌嗜神经侵袭分子机制的研究进展
Author: Mei ZHANG ¹ ; Xin-Hua LIANG ² ; Ya-Ling TANG ¹
Author Information

1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
2. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Publication Type:Journal Article
Keywords: adenoid cystic carcinoma; molecular mechanism; perineural invasion; salivary gland
From: West China Journal of Stomatology 2018;36(2):204-211
CountryChina
Language:Chinese
Abstract: Salivary adenoid cystic carcinoma is a very common malignant neoplasm in the salivary glands. One of the most important features of salivary cystic carcinoma is perineural invasion, which renders its complete removal is very difficult through clinical surgery. Consequently, tumor recurrence occurs easily after clinical surgery. Therefore, the molecular mechanisms of perineural invasion in salivary adenoid cystic carcinoma are necessary to explore. These mechanisms are reviewed in this paper.