Molecular and cell biological mechanism of olfactory adaptation in .
- Author:
Xiaoyan ZHANG
1
;
Lijun KANG
1
Author Information
1. Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou 310058, China.
- Publication Type:Journal Article
- From:
Journal of Zhejiang University. Medical sciences
2018;47(3):307-312
- CountryChina
- Language:Chinese
-
Abstract:
Olfactory adaptation is an important physiological function of animals, which can protect their own neurons from overstimulation, and be better to deal with all kinds of stimuli in the surrounding environment. In this article, we discuss the neuronal basis of olfactory adaptation in . Up to now, several intracellular regulatory factors have been discovered to be associated with olfactory adaptation in , including cyclic guanosine monophosphate (cGMP) signaling in the olfactory neurons AWC, OSM-9 in transient receptor potential vanilloid (TRPV) channel, arrestin ARR-1, diglyceride (DAG) pathway in G protein signaling pathways, etc. However, the neural circuits of the olfactory adaptation remains largely unknown. This paper reviews molecular and cell biological mechanism of olfactory adaptation in , so as to provide reference for studies on olfactory sensation in advanced animals.
