Endovascular treatment of wide-necked aneurysms using stents combined with electrolytic detachable coils in a canine model
- VernacularTitle:血管内支架结合电解可脱卸弹簧圈治疗犬颈动脉宽颈动脉瘤的实验研究
- Author:
Jianmin LIU
;
Xin ZHANG
;
Xiaoping ZHOU
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Aneurysm, embolization;
Interventional instrumentation;
Stent, coils;
Experimental, animal
- From:
Journal of Interventional Radiology
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess hemodynamics and histology of the aneurysms by treating experimental wide necked aneurysms endovascularly with a combination of stents and electrolytic detachable coils.Methods An experimental model was surgically constructed in the necks of six canines for simulating intracranial wide necked aneurysms. Balloon expandable metal stents were positioned across the aneurysms in bilateral carotid arteries of six canines with additional intraaneurysmal placement of detachable microcoils in only unilateral carotid artery of each canine. Sonography and angiography were performed in different stages and histologic examinations were achieved finally. Results Stent placement was successful in all six canines. Aneurysms treated with only stents placement showed no significant thrombus formation with slow growing of neointima over the neck of the aneurysm. Thrombosis occurred in the aneurysms treated with stents and coils in a short time and neointima covered the neck of the aneurysms completely.Conclusions Endovascular treatment of wide necked aneurysms using stents combined with electrolytic detachable coils may prevent re rupture of the aneurysms and promote neointima formation over the neck of the aneurysms.
