Valvular and perivalvular involvement in patients with chronic kidney disease
- Author:
Senkottaiyan Neelavathi
;
Hafidh Saad
;
Manian A. Farrin
;
Alpert A. Martin
- Publication Type:Journal Article
- Keywords:
Chronic kidney disease;
mitral annular calcification;
aortic valve calcification;
aortic stenosis;
infective endocarditis
- From:
Journal of Geriatric Cardiology
2005;2(3):172-177
- CountryChina
- Language:Chinese
-
Abstract:
Abstract Mitral annular calcification (MAC) and aortic valve alcification (AVC) are the most common valvular and perivalvular bnormalities in patients with chronic kidney disease (CKD). Both MAC and AVC occur at a younger age in CKD patients than in the general population. AVC progresses to aortic stenosis and mild aortic stenosis progresses to severe aortic stenosis at a more rapid rate in patients with CKD than in the general population. The use of calcium-free phosphate binders in such patients may reduce the calcium burden in valvular and perivalvular tructures and retard the rate of progression of aortic stenosis. Despite high rates of morbidity and mortality, the prognosis associated with valve surgery in patients with CKD is better than without valve surgery. Infective endocarditis remains an important complication of CKD, particularly in those treated with hemodialysis.
