Diagnostic value and clinical significance of NT-proBNP and inflammatory factors in pre-eclampsia
10.3969/j.issn.1671-8348.2017.32.021
- VernacularTitle:NT-proBNP与炎症因子在先兆子痫的诊疗价值及临床意义
- Author:
Yan SU
1
Author Information
1. 河北省唐山市妇幼保健院内科 063000
- Keywords:
NT-proBNP;
inflammatory factors;
pre-eclampsia
- From:
Chongqing Medicine
2017;46(32):4537-4539
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value and clinical significance of NT-proBNP and inflammatory factors in pre-eclampsia.Methods A total of 81 normal pregnant women was selected in the hospital from February 2015 to February 2016 as group A,81 pregnant women with mild pre-eclampsia as group B and 81 pregnant women with severe pre-eclampsia as group C.NT-proBNP and inflammatory factors detection were performed.Differences of NT-proBNP and inflammatory factors in both groups were compared.Correlation between NT-proBNP,inflammatory factors and pre-eclampsia was analyzed.Results The levels of NT-proBNP,C-reactive protein(CRP),interleukin-6 and tumor necrosis factor-α(TNF-α) were measured before and after treatment.Before treatment,with regard to those indicators,the three groups ranked in descending order were C,B,A group(P＜0.05).After treatment,with regard to those indicators which were decreased in group B and group C(P＜0.05),the three groups ranked in descending order were C,B,A group (P ＜ 0.05).Those indicators were positively correlated with pre-eelampsia (r =0.569,0.602,0.418,0.427,P=0.000).As for incidence of complications,the three groups ranked from high to low were C,B,A group (P＜0.05).Conclusion NT-proBNP and inflammatory factors have a tendency to increase in patients with pre-eclampsia,which can be used as effective indexes for the evaluation of pre-eclampsia.
