Informed consent competency and related factors in patients with schizophrenia
10.3969/j.issn.1000-6729.2017.10.006
- VernacularTitle:精神分裂症患者知情同意能力的相关因素
- Author:
Qin Xue WANG
1
;
Xin YU
;
Yu Hong TANG
;
Zhong Gui YAO
;
Qin Yue HUANG
;
Mei Tian SI
;
Tao LI
;
Ling YU
;
Jing Jing LI
Author Information
1. 北京大学第六医院(北京大学精神卫生研究所)
- Keywords:
schizophrenia;
Chinese Mandarin Version of MacArthur Competence Assessment Tool for Clinical Research;
related factors
- From:
Chinese Mental Health Journal
2017;31(10):781-787
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze related factors to the informed consent competency of patients with schizophrenia.Methods:Subjects were divided into two groups,namely one group including 100 patients with schizophrenia and the other group including 28 heathy controls.Patients with schizophrenia were administrated from community rehabilitation units and The Sixth Hospital of Peking University,diagnosed with the Diagnostic and Statistical Manual of mental disorder,Fourth Edition (DSM-Ⅳ).Informed consent competency of subjects were evaluated with the Chinese Mandarin Version of MacArthur Competence Assessment Tool for Clinical Research.Psychiatric symptoms,intelligence quotient and severity of disease were accessed individually with the Positive and Negative Symptom Scale (PANSS),Wechsler Abbreviated Scale of Intelligence (WASI) and Clinical General ImpressionSeverity Scale (CGI-S).Logistic regression analysis model was used to analyze the risk factors of impaired informed consent competency in schizophrenia.Retsrts:The rates of absent,impaired and adequate informed consent competency were 26.0％ (26/100),47.0％ (47/100) and 27.0％ (27/100) in schizophrenia group,and 3.6％ (1/28),57.1％ (16/28) and 39.3 ％ (11/28) in control group.Rate of absent informed consent competency was higher in schizophrenia group than that in control group (26.0％ vs.3.6％,P ＜0.01).There were no statistic significant differences in rates of impaired and adequate informed consent competency between two groups (both P ＞ 0.05).Results of logistic regression analysis showed that schizophrenic patients with higher scores of positive subscale (OR =1.15),negative subscale (OR =1.23) and CGI-S (OR =1.57) had more tendency to impaired capacity.Higher education level (OR =0.73) and higher scores of IQ (OR =0.92) had less risks for that.Conclusion:Competency of informed consent in schizophrenia may be worse than that in health control.Patients with schizophrenia with impaired informed consent competency may have more serious of positive,negative psychiatric symptoms and higher severity of disease.Higher level of education and IQ scores may reduce the risk of impaired informed consent competency.
