Role of Hedgehog signaling pathway in the development of retinal cells and pathological angiogenesis
10.3760/cma.j.issn.2095-0160.2017.10.019
- VernacularTitle:Hedgehog信号通路在视网膜细胞发育及病理性血管生成中的作用
- Author:
Meilin LIU
1
Author Information
1. 110004沈阳,中国医科大学附属盛京医院眼科
- Keywords:
Hedgehog signaling pathway;
Retina;
Vascular development;
Pathologic angiogenesis
- From:
Chinese Journal of Experimental Ophthalmology
2017;35(10):940-943
- CountryChina
- Language:Chinese
-
Abstract:
The pathological growth of retinal cells and ocular pathologic angiogenesis can be seen in a variety of eye diseases,which seriously affect the visual acuity of patients.The Hedgehog signal pathway has been demonstrated to be involved in the development of retinal ganglion cells,amacrine cells,cone cells and rod cells,Müller glial cells and retinal pigment epithelial cells.This paper discusses the function of Hedgehog signal pathway in the development of retinal cells and ocular pathologic angiogenesis,which may provide a new therapeutic target for retinal and ocular vascular diseases.
