Clinical application of FOLFIRINOX regimen for pancreatic cancer
10.3760/cma.j.issn.1673-422X.2017.11.018
- VernacularTitle:FOLFIRINOX方案在胰腺癌治疗中的应用
- Author:
Lan YU
1
;
Xiaotao ZHANG
;
Jinying LI
;
Yu WANG
Author Information
1. 266042,青岛大学医学院第二附属医院青岛市中心(肿瘤)医院肿瘤防治中心
- Keywords:
Pancreatic neoplasms;
Drug therapy;
FOLFIRINOX regimen
- From:
Journal of International Oncology
2017;44(11):874-878
- CountryChina
- Language:Chinese
-
Abstract:
Clinical studies have confirmed the FOLFIRINOX regimen (oxaliplatin + irinotecan + fluorouracil + leucovorin) is an effective regimen for advanced pancreatic cancer patients with good performance status.Current clinical studies on FOLFIRINOX regimen mainly include neoadjuvant therapy for unresectable and borderline resectable pancreatic cancer and first-line therapy for locally advanced pancreatic cancer and metastatic pancreatic cancer,which improved patient's surgical resection opportunities and survival.In addition,the toxicity,safety of FOLFIRINOX regimen and effective population selection for FOLFIRINOX regimen are also the problems concerned by researchers.
