Effects of laparoscopic myomectomy on gastrointestinal function recovery and changes of serum IFN-γ and angiotensin Ⅱ in postoperative patients with uterine fibroids
10.3969/j.issn.1006-5725.2017.24.027
- VernacularTitle:腹腔镜下子宫肌瘤剔除术对子宫肌瘤患者术后胃肠功能恢复及血清IFN-γ、AngⅡ水平变化的影响
- Author:
Nan CUI
1
;
Jinghong ZHANG
Author Information
1. 117000,辽宁省本溪市中心医院妇产科
- Keywords:
uterine fibroids;
laparoscopic;
myomectomy
- From:
The Journal of Practical Medicine
2017;33(24):4130-4133
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of laparoscopic myomectomy on recovery of gastrointestinal function and the changes of serum human interferon-γ(IFN-γ)and angiotensinⅡ(AngⅡ)levels in postoperative patients with uterine fibroids. Methods 79 patients were randomly divided into two groups according to different surgical procedures. The control group(39 patients)was treated with conventional open uterine myomectomy. The observation group(40 patients)was treated by laparoscopic myomectomy.The surgical situation,recovery of gastro-intestinal function,levels of serum IFN-γ,AngⅡ,ischemia modified albumin(IMA),myoglobin(MYO),and complications were compared between the two groups.Results Blood loss,pelvic drainage,discharge time,post-operative exhaust,bowel sound recovery,and postoperative defecation time were lowerin the observation group than in the control group.After one week,levels of serum IFN-γ,AngⅡ,IMA,and MYO were lower in the observation group than in the control group(P<0.05).The complication rate was lower in the observation groupthan in the con-trol group[5.00%(2/40)vs.23.08%(9/39),P<0.05].Conclusions Laparoscopic myomectomy can improve the levels of inflammatory factors and stress hormones in patients with uterine fibroids,promote the recovery of gastroin-testinal function,relieve oxidative damage,and decrease the incidence of complications.
