Mitochondrial transfer mechanism of stem cells for therapy of lung injury
10.3760/cma.j.issn.2095-4352.2018.01.017
- VernacularTitle:干细胞治疗肺损伤的线粒体转移机制
- Author:
Jinwang HAN
1
;
Yanling SONG
;
Feng ZHU
Author Information
1. 张家港广和中西医结合医院神经外科
- Keywords:
Stem cell;
Mitochondrial transfer;
Lung injury;
Gap junction channel;
Mechanism
- From:
Chinese Critical Care Medicine
2018;30(1):88-90
- CountryChina
- Language:Chinese
-
Abstract:
Stem cells transfer normal functional mitochondria to injured lung cells and reconstruct their function, which is one of the important mechanisms of stem cells in the treatment of lung injury. Mitochondrial translocation is mediated by intercellular gap junction (GJCs), which is unidirectional. This paper reviewed the research of stem cells for the treatment of lung injury mitochondrial transfer mechanism, to understand the clinical significance of lung mitochondria in physiological and pathological roles of mitochondria and transfer mechanisms of stem cells for the treatment of various types of lung injury.
