Effects of early enteral nutrition support on the clinical efficacy and surgical safety of patients with severe acute pancreatitis
10.3760/cma.j.issn.1008-6315.2018.01.010
- VernacularTitle:早期肠内营养支持治疗对重症急性胰腺炎患者临床效果及手术方式安全性的影响
- Author:
Hongwei ZHANG
1
;
Wei DING
;
Qin ZHANG
;
Bo PENG
;
Fang HU
Author Information
1. 432900,湖北省孝昌县第一人民医院重症医学科
- Keywords:
Enteral nutrition;
Severe acute pancreatitis;
Complications;
Nutritional status
- From:
Clinical Medicine of China
2018;34(1):49-53
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of early enteral nutrition support on the clinical efficacy and surgical safety of patients with severe acute pancreatitis(SAP).Methods From January 2015 to June 2017,one hundred and twenty-six cases with SAP in Xiaochang First People ′s Hospital were selected as the research object,and were randomly divided into the observation group and the control group,with 63 cases in each group.All patient were treated with CT guided puncture and drainage treatment,the control group was given postoperative parenteral nutrition support from 1 d after operation,the observation group was given postoperative nutritional support from 1 d after operation,all the nutritional support for 14 d.Results All patients completed the operation successfully and no serious complications occurred during the operation,the operation time of the observation group was(156.33±16.39)min,and the operation time of the control group was(151.02±14.99) min,the difference was not statistically significant(t=1.898,P=0.060); the intraoperative blood loss of the observation group was(45.02± 11.95)ml,and the intraoperative blood loss of the control group was(46.04 ±18.44)ml,the difference was not statistically significant(t=0.368,P=0.713); the postoperative hospital stay was(7.20±1.55)d in the observation group and(14.88±2.15)d in the control group,the difference was statistically significant(t=22.999,P=0.000);at 14d after the surgery,the observation group had 1 case of bile leakage,1 case of pancreatic pseudocyst,1 case of digestive tract fistula,at 14d after the surgery,the control group had 2 cases of hemorrhage,3 cases had bile leakage,3 cases had pancreatic pseudocyst,3 cases had digestive tract fistula,the incidence of complications was statistically significant(χ2=5.143,P=0.023);in the observation group,50 cases were cured,12 cases were improved,1 cases were ineffective,in the control group,35 cases were cured,20 cases were improved,8 cases were ineffective,the difference between the two groups was statistically significant(χ2=5.863,P=0.016);the ALB value of the observation group was(30.95±5.11)g/L at 1 d after surgery,the ALB value of the control group was(30.58 ± 6.96)g/L at 1 d after surgery,the difference was not statistically significant(t=0.340,P=0.734),the albumin value of the observation group was (36.65±3.00)g/L at 14 d after surgery,higher than that at 1 d after surgery,the difference was statistically significant(t=7.635,P=0.000),the albumin value of the control group was(33.36±3.85)g/L at 14 d after surgery,higher than that at 1 d after surgery,the difference was statistically significant(t=2.774,P =0.007), the difference in albumin value at 14d after surgery between the two groups was statistically significant(t=5.350,P=0.000);the prealbumin value of the observation group was(155.36± 52.12)mg/L at 1 d after surgery,the prealbumin value of the control group was(154.63 ± 41.96)mg/L at 1 d after surgery,the difference was not statistically significant(t=0.087,P=0.931),the Prealbumin value of the observation group was(193.52 ± 55.88)mg/L at 14 d after surgery,higher than that at 1 d after surgery,the difference was statistically significant(t=3.964,P=0.000),the prealbumin value of the control group was(171.52±50.85) mg/L at 14 d after surgery,higher than that at 1 d after surgery,the difference was statistically significant(t=2.033,P=0.044),the difference of PA value at 14 d after surgery between the two groups was statistically significant(t=2.311,P=0.022).Conclusion Early enteral nutrition support treatment of SAP can improve the clinical efficacy,reduce postoperative complications,improve the nutritional status of the body and promote the rehabilitation of patients.
