Research progress in tyrosine kinase inhibitor combined with radiotherapy for brain metastases in patients with non-small cell lung cancer

VernacularTitle:非小细胞肺癌伴脑转移患者TKI联合放疗研究进展
Author: Yue KONG ¹ ; Zhenbo SONG ; Ming CHEN
Author Information

1. 浙江省肿瘤医院放疗科浙江省放射肿瘤学重点实验室
Keywords: Lung neoplasms; Brain metastases; Tyrosine kinase inhibitor; Radiotherapy
From: Chinese Journal of Radiation Oncology 2017;26(10):1218-1221
CountryChina
Language:Chinese
Abstract: Brain metastases ( BM ) are a frequent complication of non-small cell lung cancer (NSCLC), with various treatment strategies. The widespread use of tyrosine kinase inhibitor (TKI) has significantly prolonged the survival of NSCLC patients with epidermal growth factor receptor mutations. This article reviews recent progress in TKI therapy for BM in NSCLC patients and discusses a combination of TKI and radiotherapy.