The sensitivity and specificity of CT enterography comprehensive score in evaluating the activity of Crohn's disease
10.3969/j.issn.1002-1671.2017.10.012
- VernacularTitle:CT小肠造影综合评分评价克罗恩病活动度的敏感性及特异性研究
- Author:
Xia WANG
1
;
Wendong LIU
;
Xiaoying ZHAO
;
Xingwang WU
Author Information
1. 安徽医科大学第一附属医院放射科
- Keywords:
Crohn's disease;
computed tomography;
enterography;
Crohn's disease activity index
- From:
Journal of Practical Radiology
2017;33(10):1541-1544
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of CT enterography (CTE)imaging scores in assessing the clinical activity of Crohn's disease (CD).Methods Forty-eight patients with pathologically or clinically confirmed CD were collected retrospectively.The CTE findings associated with disease activity were analyzed and scored,and the well-known Crohn's disease activity index (CDAI)was also performed.The correlation between CTE score and CDAI score was analyzed by Pearson correlation method.The diagnostic efficacy and optimal diagnostic threshold of CTE score for clinical activity of CD were evaluated by ROC curve analysis.Results There was a good correlation between the CTE score and CDAI (r =0.790,P <0.001).ROC curve analysis showed the area under the curve (AUC)was 0.913 (P <0.001).The optimal diagnostic threshold was 5.5.A CTE score of 5.5 or above indicated the disease was active,with a sensitivity of 84.2％,specificity of 80％,positive predictive value of 94.1％,negative predictive value of 57.1％ and the Youden index of 0.642.Conclusion The CTE comprehensive score has high sensitivity and specificity for estimating clinical activity of CD.
