Sclerosing Mucoepidermoid Carcinoma of the Parotid Gland.
- Author:
Soo Won HONG
1
;
Byeong Cheol LEE
;
Jae Seok LEE
;
Jae Soo KOH
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences, Seoul, Korea. bcleemd@kcch.re.kr
- Publication Type:Case Report
- Keywords:
Mucoepidermoid carcinoma;
Sclerosis;
Parotid gland
- MeSH:
Biopsy, Fine-Needle;
Carcinoma, Mucoepidermoid;
Collagen;
Female;
Follow-Up Studies;
Frozen Sections;
Humans;
Mucins;
Parotid Gland;
Salivary Glands;
Sclerosis
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2008;51(12):1170-1173
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sclerosing mucoepidermoid carcinoma of salivary gland is a rare variant of mucoepidermoid carcinoma and can be confused with benign condition on clinical, radiological, and pathologic examination. A 34-year old female was found to have a parotid mass with a long history. Preoperative evaluation including computed tomography and fine needle aspiration cytology were nondiagnostic. Intraoperatively, frozen section specimens showed only low grade tubular lesion with severe background inflammatory infiltration. Final pathological examination demonstrated multiple cystic nests composed of mucinous and squamoid intermediate cells within the background of central dense, sclerotic, collagenized stroma and peripheral inflammatory infiltrate, consistent with a low grade sclerosing mucoepidermoid carcinoma. Sclerosing mucoepidermoid carcinoma is a very rare salivary gland tumor with an uncertain clinical behavior. Complete surgical excision with tumor-free margins is recommended. Postoperative radiation therapy is suggested for positive or close margins, and close follow-up of the patients is mandatory.
