A Case of Malignant Peripheral Nerve Sheath Tumor in Nasal Cavity.
- Author:
Chan Hum PARK
1
;
Hyung Seob KIM
;
Jun Ho LEE
;
Sung Ju HONG
Author Information
1. Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Hallym University, Chuncheon, Korea. hlpch@paran.com
- Publication Type:Case Report
- Keywords:
Nasal cavity;
Malignant peripheral nerve sheath tumor
- MeSH:
Extremities;
Head;
Human Body;
Immunohistochemistry;
Incidence;
Nasal Cavity;
Neck;
Nerve Sheath Neoplasms;
Peripheral Nerves;
Recurrence;
Sarcoma
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2008;51(4):376-379
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The malignant peripheral nerve sheath tumor (MPNST) is an extremely rare soft tissue sarcoma of ectomesenchyme. It is a highly malignant sarcoma, which is locally invasive, frequently leading to multiple recurrences and eventual metastatic spread. The peak incidence of this disease is known to arise in the seventh decades. In human body, trunk and extremities are the most commonly involved site, and only 8-14% of all lesions appears in head and neck region. Because of its non-specific clinical and histopathological presentation, the diagnosis of MPNST has been described as one of the most difficult diagnosis. But this difficulty of diagnosis was solved by the use of immunohistochemistry. The authors report a case of malignant peripheral nerve sheath tumor in nasal cavity with a review of the literature.
