Second Primary Malignancies in Patients with Head and Neck Cancer.
- Author:
Se Jun CHOI
1
;
Seung Ho CHOI
;
Sang Yoon KIM
;
Soon Yuhl NAM
Author Information
1. Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. synam@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Second primary cancers;
Head and neck cancer;
Survival rate
- MeSH:
Follow-Up Studies;
Head and Neck Neoplasms*;
Head*;
Humans;
Medical Records;
Neoplasms, Second Primary;
Prevalence;
Retrospective Studies;
Survival Rate
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2006;49(2):194-198
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: A clinical study of second primary malignancies in patients with cancer of the head and neck was performed. SUBJECTS AND METHOD: Among 1741 patients with head and neck cancer, 91patients were diagnosed as second primary malignancies. We retrospectively reviewed the medical records about site, chronology, and survival. RESULTS: There was association between the sites of index and second primary malignancy. This was explained by the concept of field cancerization. Three year-survival rate was 28.6%, and second primary malignancies in the advanced stages had poor survival. However, the chronological variable was not significant. CONCLUSION: The prevalence of second primary malignancies in patients with head and neck cancer was of 5.2%. Most of them were located in the upper aerodigestive tract. Frequent and regular follow-up is important for early detection of second primary malignancies.
