Clinical profile of patients with presumptive diagnosis of leptospirosis at Corazon Locsin Montelibano Memorial Regional Hospital
- Author:
Criselda E Bacolor
;
Joan E Cerrada
;
Carina H Frayco
- Publication Type:Journal Article
- From:
Philippine Journal of Internal Medicine
2011;49(3):130-141
- CountryPhilippines
- Language:English
-
Abstract:
Background: Leptospirosis is an infectious disease of global importance. The lack of community – based prevalence studies may contribute to the fact that the disease may not be widely recognized as one of the major health problem. Objective: To establish a clinical profile of patients diagnosed with leptospirosis in CLMMRH based on the WHO Criteria from January 2006-September 2008 and to provide epidemiological data about the disease in Negros Occidental. Methodology: A retrospective study was done at Corazon Locsin Montelibano Memorial Regional Hospital (CLMMRH) from January 2006 – September 2008. Results and Conclusion: A total of 70 patients were included in the study. The Diagnosis was made based on the WHO criteria for the diagnosis of leptospirosis both clinical and epidemiological factors only, because of unavailable serologic test (MAT) in our locality. The disease affected mostly males, belonging in the age-working group. All subjects have possible exposure to contaminated water. Fever, abdominal pain, headache and calf tenderness were the most common presenting and initial signs and symptoms. Bleeding manifestations, oliguria/ anuria and jaundice are present among Weil’s syndrome cases. The degree of thrombocytopenia and its outcome showed that, among the thrombocytopenic group, 50.8% was discharged and 88.9% mortality was observed. The cities of Bacolod and Talisay and municipality of Murcia, persistently had the most admitted cases of leptospirosis. Severe form of leptospirosis is most common among municipalities in the southern part of the province. The occurrence of cases is noted to be all year round. The lack of available health care services in these areas contributed to the outcome of the disease. Early detection and prompt treatment influenced the clinical outcome of the disease.