Treatment Resistant Mania: A Case Report
- Author:
Tee Chun Keat
;
Poh Yih Chew
;
Eni Rahaiza
;
Choo Shell Pinn
;
Bilbir Kaur
- Publication Type:Case Reports
- Keywords:
Treatment Resistant Mania;
Augmentation;
Clozapine
- From:ASEAN Journal of Psychiatry
2016;17(1):1-4
- CountryMalaysia
- Language:English
-
Abstract:
Objective: The objective of this case report is to highlight the challenges faced in
managing a patient with treatment resistant bipolar mania. Methods: We report
a case of a young Chinese lady who was in the manic phase of bipolar mood
disorder and though compliant, was found to be resistant to standard anti-manic
medications that were given for a duration of 3 months. Clozapine was used as
augmentation therapy. Results: Marked clinical improvement was shown after
augmentation with clozapine. Conclusions: Clozapine appears to be effective
augmentation therapy when dealing with cases of resistant bipolar mania.
However, further in-depth studies are needed to substantiate its indication,
safety and effectiveness in such cases.
- Full text:P020160302026609501718.pdf
