Polycystic ovary syndrome: a primary follicular disorder
- VernacularTitle:多囊卵巢综合征可能是原发性卵泡病
- Author:
Strauss JEROME
- Publication Type:Journal Article
- Keywords:
Polycystic ovary syndrome;
Insulin resistance;
Follicular disorder
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovary syndrome is characterized by reproductive endocrinology and metabolic abnormalities.This paper reviewed recent advance in science frontier about PCOS including: ① PCOS manifests as primary ovary disorder;②The core features in PCOS are associated with increased size and functionalities of follicles,③ Insulin resistance constitutes the key pathophysiology of PCOS;④ Insulin sensitizing agents are effective in treating the reproductive and metabolic disorders.Thus,it is hypotheses that PCOS may be a primary disorder of follicles and perhaps a follicular disorder of insulin resistance.Such an idea offers new direction for future research for PCOS.