The influence of passive movement and electric stimulation on the bone BGP and TRACP in rats with denervation
- VernacularTitle:被动运动和电刺激对失神经大鼠骨BGP和TRACP含量的影响
- Author:
Junhan LI
- Publication Type:Journal Article
- Keywords:
Denervation;
Passive movement;
Electric stimulation;
Disuse osteoporosis;
Bone metabolism
- From:
Journal of Chongqing Medical University
2007;0(08):-
- CountryChina
- Language:Chinese
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Abstract:
Objective:To discuss the preventive function of passive movement and electric stimulation on rats with disuse osteoporosis. Methods:Through cutting the sciatic nerve and femoral nerve of experimental rats,we made an animal model of disuse osteoporosis,and divided them into five groups:the pseudo operation group,the denervation group(DG),denervation with passive movement group(PMG), denervation with electric stimulation group(ESG),and denervation with passive movement and electric stimulation group(PMESG).Then the changes of biochemistry indicators of bone metabolism were observed in all groups.Results:Compared with sham group,the Bone gla protein(BGP)value in the other groups were markedly lower(P0.05).Compared with DNG,the BGP value in the other groups increased,especially that the BGP in the PMESG was significantly increased(P