The study of the hypothalamic-pituitary-adrenal axis fuction in type 2 diabetes mellitus patients
- VernacularTitle:2型糖尿病患者的下丘脑-垂体-肾上腺轴功能研究
- Author:
Rushuang ZHANG
- Publication Type:Journal Article
- Keywords:
Type 2 Diabetes mellitus;
Hypothalamic-pituitary-adrenal axis;
Cortisol;
Saliva.
- From:
Journal of Chongqing Medical University
2007;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the function of the hypothalamic-pituitary-adrenal(HPA)axis in type 2 diabetic patients.Methods:Subjects were divided into three groups:control group(normal glucose),IGR group(IGT and/or IFG)and T2DM group.General clinical characteristics,morning cortisol concentrations(saliva and plasma)and MSCR(morning salivary cortisol rise)of the three groups were compared.Results:1)MSCR in the T2DM group was significantly lower than that in the control group(P
