A study on pathogenesis and inheritance risk of congenital mental retardation
- VernacularTitle:先天性智力低下的病因及发病风险的研究
- Author:
Yuping CUO
- Publication Type:Journal Article
- Keywords:
Mental retardation;
Monogenic disorders;
Polygenic disorders;
Chromosomal diseases
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the genetic factors relating to mental retardation (MR).Methods:We have analysed 840 cases of congenital mental retardation with biochemistry lab tests,cytogenetic study and family investigation.Results:21 cases were due to monogenic disorders (2.50%);216 cases were due to chromosomal diseases (25.71%);13 cases were due to polygenic disorders (1.55%);590 cases were due to unknown causes (70.24%).Conclusion:It suggested that occurrence of mental retardation is related to both genetic factors and environmental factors.
