Progress of autoimmune lymphoproliferactive syndrome
10.3760/cma.j.issn.1673-4408.2010.04.010
- VernacularTitle:自身免疫性淋巴细胞增生综合征研究进展
- Author:
Zhenli CHENG
- Publication Type:Journal Article
- Keywords:
Autoimmunity;
Apoptosis;
FAS gene;
Double negative T cell
- From:
International Journal of Pediatrics
2010;37(4):365-367,371
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune lymphoproliferactive syndrome is a rare group disorders associated with self stability and immune tolerance of lymphocyte due to genetic mutation which affects the lymphocyte apoptosis .The clinical manifestations comprise lymphoproliferation, development of autoimmunity and malignancies.The pathogenesis and clinical features are complex ALPS were easily missed and no case had been reported until now in China.
