Expression of MMP-2 and MMP-7 in colon adenoma and colon cancer
- VernacularTitle:结肠肿瘤组织中MMP-2和MMP-7表达的临床研究
- Author:
Huaisheng CAI
- Publication Type:Journal Article
- Keywords:
Colon neoplasms?Matrix metalloproteinases
- From:
Chinese Journal of Current Advances in General Surgery
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the expression of matrix metalloproteinase- 2(MMP- 2) and matrix metalloproteinase- 7(MMP- 7)in colon adenoma and colon cancer. Methods: Forty tis-sue samples of colon adenoma and 60 of colon cancer were collected .Normal colonic tissues were also collected from the same subjects. The mRNA expression levels of MMP- 2 and MMP- 7 were quantitated using semiquantitative reverse transcription polymerase chain reactions. Results: The expression level of MMP- 2 in the colon adenoma was higher than that in the normal colonic tissues (P