Lacunar infarction:a hemodynamic analysis of 102 cases
- VernacularTitle:腔隙性脑梗死102例患者的脑血流动力学分析
- Publication Type:Journal Article
- Keywords: Brain infarction; Cerebral angiography; Tomography,X-ray computed; Hemodynamic phenomena
- From: Chinese Journal of Neurology 2005;0(09):-
- CountryChina
- Language:Chinese
- Abstract: Objective To study cerebrovascular lesion and lacunar infarction(LI)and to explore the pathogenesis of LI based on neuroradiological imaging.Methods Brain MRI、CT angiography(CTA) and CT perfusion(CTP)were performed in all 102 patients with LI.Results MRI showed single LI in 3 cases,multiple LI in 99 cases.CTA showed severe stenosis or occlusion of internal carotid artery(ICA)in 32 cases,severe stenosis or occlusion of middle cerebral artery(MCA)in 11 eases,moderate or mild ICA stenosis in 19 and moderate or mild MCA stenosis in 5.CTA also showed significant ICA and MCA atheroselerosis in 23.CTP showed that all 56 patients had hypoperfusion areas in regions supplied by ICA or MCA.Hypoperfusion more frequently occurred in patients with severe ICA stenosis than in patients with moderate or mild carotid stenosis and it occurred in all patients with MCA stenosis.Most of LI occurred in these hypoperfusion areas.Conclusions LI shown in imaging may be caused by hypoperfusion or microemboli in distal arteriola resulted from stenosis or occlusion in large proximal arteries.