EFFECT OF THYROID HORMONE DEFICIENCY ON TUBULIN SYNTHESIS IN THE DEVELOPING EMBRYONIC CHICK BRAIN
- VernacularTitle:甲状腺激素缺乏对胚胎发育期间脑微管蛋白合成的影响
- Author:
Shouxiang GUO
- Publication Type:Journal Article
- Keywords:
Tubulin Thyroid hormone Chick embryo
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
The thyroid hormone deficiency was made in chick embryos by injecting propyl-thiouracil (PTU). The tubulinwas quantitated by 3H-colchicinc assay (expressed as colchicine binding activity). Thyroid hormone deficiency resultedin a 16% to 28% decline of the tubulin level in the developing chick brain from 15 to 19 days of embryonic age as compared with the control, whereas the total protein amount was not significantly affected.
