Prediction of Chemosensitivity Test on Human Pancreatic Carcinoma Cells of Short-Term Culture in Vitro
- VernacularTitle:人胰腺癌体外抗肿瘤药物敏感性分析研究
- Author:
Fanhong MONG
- Publication Type:Journal Article
- Keywords:
Chemotherapy;
Carcinoma of the pancreas;
Chemosensitivit;
Test in vitro
- From:
Journal of Kunming Medical University
1989;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
In this paper the experimental study and clinical preliminary observation of chemosensitivity test on 5 cases of pancreatic carcinoma in vitro are reported. The major drug of clinical treatment of pancreatic carcinoma was 5-FU. The results showed only two cases had good correlativity. The results of chemosensitivity test showed that drug sensitivity inten- sity was ordinally 5-FU, MMC, ADR and TSPA. A close correlation between clinical chemotherapy treatment and chemosensitivity test in vitro was found in 4 patients out of 5. The survival time was over one year and the clinical response rate was 80%. This method could help select drug for clinical treatment and specify the application of the drug, which will surely improve the survival rate.
