Research progress of bortezomib-induced peripheral neuropathy
10.3760/cma.j.issn.1006-9801.2014.09.018
- VernacularTitle:硼替佐米所致周围神经病变的研究进展
- Author:
Hengfei DU
- Publication Type:Journal Article
- Keywords:
Bortezomib;
Multiple myeloma;
Peripheral neuropathy
- From:
Cancer Research and Clinic
2014;26(9):638-640
- CountryChina
- Language:Chinese
-
Abstract:
Proteasome inhibitor bortezomib has been used to treat various of tumors,its most important side effect is peripheral neuropathy,which limits its clinical application.This paper briefly described the etiology and risk factors of bortezomib-induced peripheral neuropathy (BIPN),the pathological mechanism,the clinical manifestation,the method of detection and evaluation.And the prevention and treatment of BIPN are introduced.