Non-umbilical Cutaneous Metastasis of Pancreatic Adenocarcinoma as the First Clinical Manifestation: A Case Report.
10.4166/kjg.2016.68.4.221
- Author:
Ji In MOON
1
;
Ji Young PARK
;
Tae Joo JEON
;
Jung Min CHOI
;
Won Chang SHIN
;
June Min SUNG
;
Young Moon KIM
;
Hyun Jung KIM
Author Information
1. Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. human@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Pancreatic neoplasms;
Cutaneous;
Neoplasm metastasis;
Immunohistochemistry
- MeSH:
Adenocarcinoma*;
Aged, 80 and over;
Biopsy, Fine-Needle;
Female;
Head;
Humans;
Immunohistochemistry;
Keratins;
Life Expectancy;
Lymph Nodes;
Neoplasm Metastasis*;
Pancreatic Neoplasms;
Scalp
- From:The Korean Journal of Gastroenterology
2016;68(4):221-224
- CountryRepublic of Korea
- Language:English
-
Abstract:
Non-umbilical cutaneous metastases from pancreatic adenocarcinomas are extremely rare. Only a few cases have been reported in the literature. An 83-year-old Korean woman, with no previous medical history, presented with a painful nodule on her scalp. Histologic examination of the nodule revealed a metastatic adenocarcinoma, and immunohistochemical staining was positive for cytokeratin (CK) 7 and CK 19. These findings were consistent with a metastatic carcinoma of pancreatic origin. An abdominal computed tomography scan identified a mass on the pancreatic head and multiple enlarged lymph nodes. Pathological examination of an endoscopic ultrasound-guided fine needle biopsy of the pancreatic mass determined that it was a poorly differentiated carcinoma. The patient refused any treatment owing to her old age and short life expectancy. Four months later, the disease progressed rapidly, and the patient died.