Study on serum levels of lipids and bilirubin in patients with coronary heart disease
- VernacularTitle:冠心病患者血脂和胆红素变化的研究
- Author:
Guanghai WEI
- Publication Type:Journal Article
- Keywords:
Cholesterol;
Bilirubin;
Coronary disease
- From:
International Journal of Laboratory Medicine
2008;29(9):789-791
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of the levels of serum lipids and bilirubin with occurrence and development of coronary heart disease (CHD). Methods 139 CHD patients and 118 healthy controls were involved in the study. The serum levels of triglyeride (TG), total cholester-ol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C)and bilirubin were measured and compared. Results In CHD group, the levels of TG, TC, LDL-C,TG, HDL-C, LDL-C and HDL-C were significantly elevated, while the levels of HDL-C, total biliru-bin (Tbil) and indirect bilirubin (Ibil) were markedly declined. The changes were associated with the severity of coronary artery disease. There wasn't significant difference of direct bilirubin level between CHD group and healthy control group. Conclusion Blood lipid abnormality and declination of bilirubin level are closely associated with coronary heart disease. It is possible to prevent the occurrence of car-diovascular event by early intervention.