Effect of hydrostatic pressure on ultrastructure of synovial fibroblasts from rat temporomandibular joint
10.3321/j.issn:1002-0098.2008.12.014
- VernacularTitle:压力作用下大鼠颞下颌关节滑膜细胞超微结构的变化
- Author:
Meng-Jie WU
1
;
Jian-Ying FENG
;
Zhi-Yuan GU
Author Information
1. 浙江大学医学院附属口腔医院
- Keywords:
Temporomandibular joint;
Synovial fibroblasts;
Pressure
- From:
Chinese Journal of Stomatology
2008;43(12):754-755
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of apoptosis in the remodeling of temporomandibular ioint(TMJ)under pressure.nethods Synovial fibroblaslt obtained from rat temporomandibular joint were subiected to different hydrostatic pressure for 12 h. Changes of uhrastmeture were observed by transmission electron microscope.Results At 30 kPa,the uhlastructure of synovial fibroblasit showed no obvious changes.At 60 kPa.the chromatin was condensated,the karyon took on crescent and the mitochondria seemed varicose.At 90 kPa,the apoptosis-like body was wrapped by membrane and embedded in the high density chromatin.Condusions Apoptosis-like change took place in ultrastructure of synodal fibroblasts under hydrostatic pressure,and the degree of the change was related to the hydrostatic pressure exerted.
