Diagnosis value of electrocardiogram in patients with pulmonary artery hypertension
10.3760/cma.j.issn.0253-3758.2010.04.017
- VernacularTitle:心电图对肺动脉高压的诊断价值探讨
- Author:
Qin-Hua ZHAO
1
;
Xi-Qi XU
;
Zhi-Cheng JING
;
Ming-Li SUN
;
Li-Zhi DAI
;
Wen-Hui WU
;
Xin JIANG
;
Jing HE
;
Yun LI
Author Information
1. 同济大学附属上海市肺科医院
- Keywords:
Hypertension,pulmonary;
Electrocardiography;
Hemodynamic processes
- From:
Chinese Journal of Cardiology
2010;38(4):346-349
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To analyze the diagnostic value of electrocardiogram (ECG) in patients with pulmonary artery hypertension (PAH) confirmed by right-heart catheterization (RHC).Methods A total of 64 patients with suspected PAH[sPAP≥36 mm Hg(1 mm Hg =0.133 kPa) estimated by echocardiography]were enrolled in this study.All patients were examined by 12-lead ECG within half an hour before RHC.Results PAH was excluded in 26 patients and confirmed in 38 patients.ECG analysis showed that S amplitude＞0.21 mV in lead Ⅰ ,QRS axis＞87°,R_(v1) + S_(v5)＞0.76 mV were good parameters for diagnosing PAH with sensibility and specificity of 89%,81%;86%,92%;84%,83%,respectively.QRS axis was positively correlated with mean pulmonary artery pressure (mPAP) (r = 0.75,P＜0.001),R_(v1) + S_(v5) was positively correlated with pulmonary vascular resistance (PVR) (r =0.74,P＜0.001),R_(v1) + S_(v5) and S amplitude in lead Ⅰ was negatively correlated with cardiac index (CI)(r = -0.62,P ＜0.001).Conclusion ECG combined with echocardiography are adequate screening tools to rule out the presence of PAH.QRS axis,R_(v1) + S_(v5) and S amplitude in lead Ⅰ were significantly correlated with hemodynamic parameters derived from RHC in PAH patients.
