Bio-adhesive drug delivery system and its application in traditional Chinese medicine.
10.19540/j.cnki.cjcmm.20171026.001
- Author:
Peng-Yue LI
1
;
Shou-Ying DU
1
;
Yang LU
1
;
Xiao-Nan CHEN
1
Author Information
1. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.
- Publication Type:Journal Article
- Keywords:
adhesive material;
bio-adhesive drug delivery system;
evaluation method;
muco-adhesion theory
- From:
China Journal of Chinese Materia Medica
2017;42(24):4687-4693
- CountryChina
- Language:Chinese
-
Abstract:
Bio-adhesive drug delivery system (BDDS) is a novel drug delivery system, which can prolong the retention time of the preparation, improve the stability of the drug, and improve the mucosa absorption and the targeting of the drug. With the development of polymer materials over the past 30 years, BDDS made a great progress. This paper reviews the muco-adhesion theory, adhesive materials, and methods to evaluate muco-adhesive properties and applications in traditional Chinese medicine according to domestic and foreign literatures, in order to provide new ideas for further studies.