Risk factors and coronary angiography characteristics of female patients with acute coronary syndrome
10.3760/cma.j.issn.0253-3758.2012.11.001
- VernacularTitle:女性急性冠状动脉综合征的危险因素与冠状动脉造影特征
- Author:
Wangle-Xian SUN
1
;
Jian-Hua YAN
;
Xiao-Yi ZHAO
;
Yan-Ping RUAN
;
Zhong-Jie FAN
Author Information
1. 河北省承德医学院附属医院心脏科
- Keywords:
Coronary artery disease;
Women;
Risk factors;
Coronary angiography
- From:
Chinese Journal of Cardiology
2012;40(11):897-901
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the risk factors and coronary angiography characteristics of female patients with acute coronary syndrome (ACS).Methods A total of consecutive 986 inpatients with ACS who had undergone coronary angiography from March 2009 to August 2010 in our hospital were enrolled in this study.There were 303 female patients and 683 male patients.Clinical data were collected by physicians and the severity of coronary artery stenosis was analyzed via the international Gensini Score system.Results Incidence of ACS under the age of 60 years [8.6％ (26/303) vs.16.5％ (113/683),P ＜ 0.05],family history of coronary artery disease [15.8％ (48/303) vs.23.0％ (157/683),P ＜ 0.05],and smokers [19.1％ (58/303) vs.71.7％ (490/683),P ＜0.001] were significantly less while hypertension [81.5％(247/303) vs.64.0％ (437/536),P ＜0.001] and diabetes rate [51.8％ (157/303) vs.44.0％ (298/683),P ＜0.05] were significantly higher in female patients than in male patients.The comorbidities of dyslipidemia,adiposity,hyper-C-reaction protein and hyperfibrinogenemia were similar between male and female patients (P ＞ 0.05).Unstable angina and non-ST-segment elevation myocardial infarction were more often [86.1％ (261/303) vs.78.5％ (536/683)],while ST-segment elevation myocardial infarction was less [13.9％ (42/303) vs.21.5％ (147/683),P =0.005] in female patients than in male patients.There were significantly more incidence of mild coronary artery stenosis [15.0％ (47/303) vs.10.0％ (68/683),P =0.012] and less severely stenotic lesions [84.2％ (255/303) vs.89.8％ (613/683),P =0.013] in female patients than in male patients.Gensini score,percutaneus intervention rate and in-hospital mortality rate were similar between male and female patients with ACS (P ＞ 0.05).Conclusions Prevalence rates of diabetes mellitus and hypertension are higher while positive family history on coronary artery disease and smoking rate are lower in female patients with ACS than in male ACS patients.Female ACS patients are often presented with unstable angina or non-ST-segment elevation myocardial infarction and with mild coronary artery stenosis compared to male ACS patients.
