To explore the safety testing evaluation index of breast-feeding by hepatitis B-positive mothers

VernacularTitle:探讨携带乙型肝炎病毒产妇母乳喂养安全性检测评价指标
Author: Wen-Ping ZHANG ¹ ; He-Ying SHI ; Cai-Bin LI ; Qi-Hong LI ; Peng DU
Author Information

1. 318020,浙江省台州市黄岩区妇幼保健院
Keywords: Hepatitis B; Pregnancy; Serum/breast milk; Hepatitis B e antigens; DNA; Breast feeding
From: Chinese Journal of Experimental and Clinical Virology 2013;27(3):202-203
CountryChina
Language:Chinese
Abstract: Objective To explore the safety testing evaluation index of breast-feeding by hepatitis B-positive mothers.Methods HBV DNA from serum and breast milk of 252 hepatitis B-positive mothers were detected with the real-time quantitative PCR.Results The total positive rate of HBV DNA in serum had no difference with that in breast milk in hepatitis B-positive mothers (P ＞ O.05).The positive rate of HBV DNA in serum and breast milk of positive HBeAg were significantly higher than that of hepatitis Bpositive mothers with negative HBeAg (P ＜ 0.01).Conclusion To detecte HBeAg and HBV DNA in serum and breast milk have important significance for guiding of breast feeding of hepatitis B-positive mothers.