Glucose-6-phosphate dehydrogenase deficiency: report of 4 cases.
- Author:
Moon Kyu KIM
1
;
Chang Hyun YANG
;
Shin Heh KANG
;
Chuhl Joo LYU
;
Kir Young KIM
Author Information
- Publication Type:Case Reports
- Keywords: G6PD deficiency
- MeSH: Child; Child, Preschool; *Glucosephosphate Dehydrogenase Deficiency/diagnosis/genetics; Humans; Male; Pedigree
- From:Journal of Korean Medical Science 1992;7(1):71-75
- CountryRepublic of Korea
- Language:English
- Abstract: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common hereditary enzyme disorder and more than 200 million people have a deficiency in this enzyme. It is a globally important cause of neonatal jaundice and causes life-threatening hemolytic crisis in childhood. At later ages, certain drugs such as antimalarials, and fava beans cause hemolysis among G6PD deficiency patients. The frequency and severity is influenced by genetic and cultural factors. It is common in Mediterranean, African, and some East Asian populations but rare in Korea. Four cases of G6PD deficiency which were first noticed in Korea are investigated with their clinical features.
