A Hypereosinophilic Syndrome with Cardiac Involvement from Thrombotic Stage to Fibrotic Stage.
10.4250/jcu.2015.23.2.100
- Author:
Nam Kyun KIM
1
;
Chang Yeon KIM
;
Jae Hee KIM
;
Se Yong JANG
;
Myung Hwan BAE
;
Jang Hoon LEE
;
Dong Heon YANG
;
Hun Sik PARK
;
Yongkeun CHO
;
Shung Chull CHAE
Author Information
1. Division of Cardiology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. scchae@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Hypereosinophilic syndrome;
Thrombotic stage;
Fibrotic stage;
Mitral regurgitation
- MeSH:
Dyspnea;
Edema;
Follow-Up Studies;
Heart Injuries;
Humans;
Hypereosinophilic Syndrome*;
Male;
Middle Aged;
Mitral Valve Insufficiency;
Mortality
- From:Journal of Cardiovascular Ultrasound
2015;23(2):100-102
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cardiac involvement is a major cause of morbidity and mortality in hypereosinophilic syndrome (HES). It is classified into 3 stages by the degree of eosinophils-mediated heart injury; acute necrotic stage, thrombotic stage, and fibrotic stage. Nonetheless, definitive evidence that each patient passes sequentially through these stages is lacking. We present a case of 48-year-old male patient with dyspnea and peripheral edema who underwent valve replacement surgery due to severe mitral regurgitation. After the valve replacement, HES with cardiac involvement in the thrombotic stage was diagnosed. In the follow-up study, the patient progressed into fibrotic stage of HES.