RASSF2A Promoter Methylation in Hepatitis B Virus-related Hepatocellular Carcinogenesis and Its Correlation with Elevated Serum α-Fetoprotein Level
10.1007/s11596-009-0309-8
- Author:
REN JINGHUA
1
;
HE WENSHAN
;
ZHANG RUIGUANG
;
LI ZHENYU
;
CAO WENMIAO
;
YAO JIE
;
ZHU FANG
;
ZHANG TAO
;
WU GANG
Author Information
1. Department of Cancer Center, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
- Keywords:
RASSF2A;
epigenetic inactivation;
hepatocellular carcinoma
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2009;29(3):309-312
- CountryChina
- Language:Chinese
-
Abstract:
is and K-ras mutation. It was concluded that aberrant methylation of the RASSF2A gene with the subsequent loss of RASSF2A expression plays an important role in the pathogenesis of HCC.
