Application progress on near infrared spectroscopy in quality control and process monitoring of traditional Chinese medicine.
- Author:
Wenlong LI
1
;
Haibin QU
2
Author Information
1. Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China.
2. Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China. quhb@zju.edu.cn.
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
standards;
Medicine, Chinese Traditional;
methods;
standards;
Pharmaceutical Preparations;
standards;
Quality Control;
Spectroscopy, Near-Infrared;
methods;
standards
- From:
Journal of Zhejiang University. Medical sciences
2017;46(1):80-88
- CountryChina
- Language:Chinese
-
Abstract:
The industry of traditional Chinese medicine (TCM) encounters problems like quality fluctuation of raw materials and unstandardized production process. Near infrared (NIR) spectroscopy technology is widely used in quality control of TCM because of its abundant information, fast and nondestructive characters. The main applications include quantitative analysis of Chinese medicinal materials, intermediates and Chinese patent medicines; the authenticity of TCM, species, origins and manufacturers; monitoring and control of the extraction, alcohol precipitation, column chromatography and blending process. This article reviews the progress on the application of NIR spectroscopy technology in TCM field. In view of the problems existing in the application, the article proposes that the standardization of NIR analysis method should be developed according to specific characteristics of TCM, which will promote the application of NIR technology in the TCM industry.