A new triterpenoid saponin from stems of Akebia trifoliata.
- Author:
Hui-min GAO
1
;
Zhi-min WANG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, Gel; Crystallization; Magnoliopsida; chemistry; Molecular Structure; Plant Stems; chemistry; Plants, Medicinal; chemistry; Saponins; chemistry; isolation & purification; Silica Gel; Silicon Dioxide; Triterpenes; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2006;41(9):835-839
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the chemical constituents of the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd.
METHODSThe compounds were isolated and purified by recrystallization and chromatography on silica gel and ODS column. Their structures were elucidated on the basis of physicochemical properties and spectral analysis.
RESULTSSix compounds were identified as 2 alpha, 3 beta,23-trihydroxyolean-12-en-28-oic acid O-beta-D-xylopyranosyl-(1 --> 3)-O-alpha-L-rhamnopyranosyl-(1 --> 4)-O-beta-D-glucopyranosyl-(1 --> 6)-beta-D-glucopyranosyl ester (I), 2 alpha, 3 beta, 23-trihydroxyurs-12-en-28-oic acid O-beta-D-xylopyranosyl-(1 --> 3)-O-alpha-L-rhamnopyranosyl-(1 --> 4)-O-beta-D-glucopyranosyl-(1 --> 6 )-beta-D-glucopyranosyl ester (II), 2 alpha, 3 beta, 23-trihydroxyolean-12-en-28-oic acid O-alpha-L-rhamnopyranosyl-(1 --> 4)-O-beta-D-glucopyranosyl-(1 --> 6)-beta-D-glucopyranosyl ester (III), 2alpha, 3beta, 23-trihydroxyurs-12-en-28-oic acid O-alpha-L-rhamnopyranosyl-(1 --> 4)-O-beta-D-glucopyranosyl-(1 --> 6)-beta-D-glucopyranosyl ester (IV), 2 alpha, 3 beta, 23-trihydroxyolean-12-en-28-oic acid O-beta-D-glucopyranosyl ester (V), 2 alpha, 3 alpha, 23-trihydroxyurs-12-en-28-oic acid O-beta-D-glucopyranosyl ester (VI).
CONCLUSIONCompound II, named mutongsaponin C, is a new triterpenoid saponin and others were isolated from the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd for the first time.
