Assessment of Therapeutic Response of Ablated Lesion after Radiofrequency Ablation in Patients with Unresectable Lung Malignancies by Multiphase Contrast-enhanced MRI.
10.13104/jksmrm.2011.15.3.200
- Author:
Gong Yong JIN
1
;
Young Min HAN
;
Gyung Ho CHUNG
;
Seung Bae HWANG
;
Yong Chul LEE
;
Keun Sang KWON
Author Information
1. Department of Radiology, Chonbuk National University Medical School and Hospital, Research Institute of Clinical Medicine, Korea. gyjin@chonbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Lung neoplasms;
Radiofrequency (RF) ablation;
Magnetic resonance imaging (MRI)
- MeSH:
Follow-Up Studies;
Humans;
Lung;
Lung Neoplasms;
Recurrence
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2011;15(3):200-207
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We evaluated which phase was important to recognize local progression of an ablated zone after RFA on multiphase contrast-enhanced MRI (CE-MRI) in patients with unresectable lung malignancy. MATERIALS AND METHODS: Twenty patients who had unresectable lung malignancy underwent multiphase CE-MRI examinations immediately after RFA. We evaluated the enhancement patterns of the ablated zone on multiphase CE-MRI: type I, no enhancement of the ablated zone; type II, enhancement of the ablated margin; type III, heterogeneous enhancement of the ablated zone. We evaluated the association enhancement type with local progression of the ablated zone on the follow up CT using Spearman's ranked test. RESULTS: In complete ablation, the enhancement pattern was types I (11.1%) or II (88.9%). In unsuccessfully treated, type II (57.1%) or III (42.9%) pattern observed in the arterial phase. However, types II (21.4%) and III (78.6%) observed in the venous, and types II (7.1%) and III (92.9%) observed equilibrium phases. Local progression of the ablated zone was associated with the enhancement pattern in equilibrium phases (r=0.8, p < .05). CONCLUSION: Equilibrium phases on multiphase CE-MRI might play a more important role in evaluating an ablated zone for predicting local recurrence after RFA.
