Analysis of saponins in Panax notoginseng by UPLC-LTQ-Orbitrap MS/MS.
- Author:
Wen XU
1
;
Xiao-Hui QIU
;
Jing ZHANG
;
Da-Yuan ZHU
;
Yi-Ming YANG
;
Chuan-Jian LU
Author Information
1. The Second College of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangdong Province Institute of Chinese Medicine, Guangzhou 510006, China.
- Publication Type:Journal Article
- MeSH:
Chromatography, High Pressure Liquid;
Fourier Analysis;
Ginsenosides;
analysis;
Panax notoginseng;
chemistry;
Plant Roots;
chemistry;
Plants, Medicinal;
chemistry;
Quality Control;
Saponins;
analysis;
classification;
Tandem Mass Spectrometry
- From:
Acta Pharmaceutica Sinica
2012;47(6):773-778
- CountryChina
- Language:Chinese
-
Abstract:
A method for qualitative analysis of constituents in Panax notoginseng by UPLC-LTQ-Orbitrap mass spectrometry was established. Based on the high-resolution mass information, MS/MS fragmentation behaviors and chemical components from literatures, 43 compounds were identified or tentatively characterized. New type saponin aglycone, combined with malonyl-substituted and acetyl-substituted saponins were discovered and plausibly identified in this study. This work could be helpful for the quality control and further phytochemical studies of Panax notoginseng, and provided a good example for the analysis of chemical constituents in traditional Chinese medicine.
