Analysis of quality of life in elderly patients with coronary artery disease after drug-eluting stent implantation
10.3760/cma.j.issn.0253-3758.2012.02.003
- VernacularTitle:老年冠心病患者药物洗脱支架置人术后生命质量的比较分析
- Author:
Chao XUE
1
;
Da-Yi HU
Author Information
1. 北京大学人民医院
- Keywords:
Coronary disease;
Stents;
Quality of life
- From:
Chinese Journal of Cardiology
2012;40(2):94-98
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the change of quality of life (QOL) between elderly ( ≥65years) and non-elderly ( ＜ 65 years) coronary artery disease (CAD) patients after drug-eluting stents (DES) implantation.Methods Patients with CAD treated with DES between March 2009 and January 2010were enrolled.All patients were prospectively interviewed at baseline and 6-month after DES implantation.Changes of overall health perception between the elderly and non-elderly patients were compared by using validated questionnaire ( SF-36 health survey).Results Scores for physical component summary (PCS)and mental component summary (MCS) were significantly worse in elderly patients than in non-elderly patients both at baseline and 6 months after DES implantation (baseline:45.3 ± 16.2 vs.55.6 ± 22.2,61.7 ± 21.5 vs.65.6 ± 17.9 ; 6-month:55.4 ± 19.9 vs.66.7 ± 18.1,65.9 ± 19.8 vs.73.6 ± 16.8,all P ＜ 0.05).QOL improved significantly after DES implantation for all eight scales and PCS as well as MCS in both age groups ( all P ＜ 0.01 ).The change of PCS score was similar between the two age groups(10.92 ±7.62 vs.10.53 ±6.81,P =0.43).Physiological function [22.11 (10.28 to 41.49) vs.11.13( -0.23 to 19.65),P ＜0.01 ] improvement was better but the change of physical function,body pain and general health [6.65 ±2.45 vs.7.65 ±2.16,10.61(4.38 -14.47) vs.21.20(11.81 to 31.14),2.10 ( -2.30 to 5.70) vs.4.72(2.28 to 6.74),all P ＜0.01 ] were worse in elderly patients than in non-elderly group.The improvement of MCS in non-elderly group was superior to elderly group [ 6.43 ( 3.11 to 8.70)vs.5.52 ( - 1.01 to 9.33 ),P ＜ 0.01 ] exampled by social function [ 8.14 (3.53 to 14.03 ) vs.1.74( - 1.73 to 6.79) ] and mental health score [ 1.26 (0.61 to 7.15 ) vs.0.81 (0.59 to 7.18 ),all P ＜0.01 ].Conclusion QOL is significantly improved in both elderly and non-elderly CAD patients after DES implantation.Improvement in physical health is similar between the two age groups,but the improvement of mental health is more significant in non-elderly patients than in elderly CAD patients.
